AWARDS & GRANTS
The Hirshberg Foundation awards the best abstract presentations during the national meeting of the American Pancreatic Association. The 2008-2009 awardees are:
BEST CLINICAL ABSTRACT
Presented to: Dr. Andrew Biankin, from Sidney, Australia
Abstract Title: "Expression of S100A2 Calcium-Binding Protein Predicts Response to Pancreatectomy for Pancreatic Cancer.” The abstract is published in Pancreas 37:462, 2008.
BEST BASIC/EXPERIMENTAL ABSTRACT
Presented to: Dr. Seunguk Oh, from University of Minnesota
Abstract Title: ““Potent and Prolonged Therapeutic Activity of Recombinant Bispecific Ligand-Directed Toxin (BLT), DTEGF13 Against Orthotopic Pancreatic Cancer in Nude Mice.” The abstract is published in Pancreas 37:488, 2008.
At the national level, the Foundation has launched a very successful seed grant program to fund pilot feasibility studies that can then go on to qualify for National Institutes of Health grants. The 2008-2009 pilot feasibility awards were given to the following individuals:
Jonathan Cheng, MD
Medical Oncology, Fox Chase Cancer Center
Title: "Tumor Stromal Fibroblastsas Therapeutic Target"
Wai-Nang Paul Lee, MD
LABiomedical Research Institute
Harbor-UCLA Medical Center
Title:”Proteomics of Pancreatic Cancer: determination of protien turnover"
Shuping Vicent Wu, PhD
VA, Greater Los Angeles HealthCare System
CURE Bldg. 115, Rm 217 VAGLAHS
Title:” Stress and Pancreatic Cancer: Role of Corticotropin Releasing Factor
(CRF) System
The Hirshberg Foundation awards the best abstract presentations during the national meeting of the American Pancreatic Association. The 2007-2008 awardees are:
BEST CLINICAL ABSTRACT
Presented to: Rahul Pannala
Abstract Title: “Traditional Diabetes Risk Factors in Pancreatic Cancer Associated Diabetes (PACDM): A Prospective Study of 512 Patients”
BEST BASIC/EXPERIMENTAL ABSTRACT
Presented to: Sushovan Guha
Abstract Title: “Tissue Transglutaminase Downregulation potentiates gemcitabine efficacy and blocks pancreatic cancer growth in vivo”
At the national level, the Foundation has launched a very successful seed grant program to fund pilot feasibility studies that can then go on to qualify for National Institutes of Health grants. The 2007-2008 pilot feasibility awards were given to the following individuals:
Edward Garon, MD
University of California, Los Angeles Title: Clinical Trial of Gemcitabine with Genisten or Placebo After Resection for Pancreatic Adenocarcinoma”
Hongxiang Hui, MD, PhD
University of California, Los Angeles
Title:”Glucagon-Like Peptide-1 is a Promising Anti-pancreatic Cancer Stem Cell Agent by Cell-differentiation Induction and Growth Inhibition”
Ashok Saluja, PhD
University of Minnesota
Title:” The Inhibition of HSP70 Expression Sensitizes Pancreatic Cancer Cells to TRAIL-Induced Apoptotic Cell Death”
Frank A. Sinicrope, MD
Mayo Clinic and Mayo College of Medicine
Title: “BH3 Mimetic Reverses Apoptosis Resistance in Human Pancreatic Cancer Cells”
David Dawson, MD
University of California, Los Angeles
Title: UCLA Pancreatic Tissue Bank and Data System, Including Microarray of the Tissue”
The Hirshberg Foundation awards the best abstract presentations during the national meeting of the American Pancreatic Association. The 2006-2007 awardees are:
M. Apte, Pancreatic Research Group, The University of New South Wales, Sydney, Australia
"Pancreatic Stellate cells Stimulate Pancreatic Cancer Growth and Metastasis: Findings of a Novel Orthotopic Model of Pancreatic Cancer" Pancreas 33(4):472, 2006
Sultana, Division of Surgery and Oncology, Royal Liverpool University Hospital, Liverpool, UK "Meta-Analyses of the Management of Locally Advanced and Metastatic Pancreatic Cancer" Pancreas 33(4):499, 2006
At the national level, the Foundation has launched a very successful seed grant program to fund pilot feasibility studies that can then go on to qualify for National Institutes of Health grants. The 2006-2007 pilot feasibility awards were given to the following individuals:
Kristina Kisfalvi, MD, PhD - UCLA Division of Digestive Diseases
Title: Role of protein kinase D (PKD) in the proliferation of pancreatic cancer cells
Harold Frucht, MD - Columbia University, New York, NY
Title: Pancreatic Physiology in the Screening and Early Detection of Human Pancreatic Adenocarcinoma
Christopher Wolfgang, MD - Johns Hopkins University, Baltimore, MD
Title: Targeting Lipid Mediations of Pancreatic Cancer Growth
Diane M. Harris, PhD - UCLA Center for Human Nutrition
Title: Fatty Acid Synthase Inhibitors in Pancreatic Cancer
Joseph Kim, MD - City of Hope National Medical Center & Beckman Research Institute, Duarte,CA
Title: Targeting Chemokine Receptor CXCR4 to Prevent Pancreatic Cancer
Over the years the pilot feasibility program has resulted in some key NIH funding, which is typically for 2 to 5 years, and these include:
Guido Eibl, MD
R01 CA 104027 - The Role of COX2 and PPAR-g in Pancreatic Cancer
Anna Gukovskaya, PhD
R01 CA 119025-01 - NADPH Oxidase and Pancreatic Cancer Cell Survival
Nathan R. Wall, PhD
P20 MD 001632-02 - Project 3, Oxidative Stress-Induced Cellular Survival Pathways in Pancreatic Cancer
Aurelia Lugea, PhD
R03 AA 016008 - Urokinase-Type Plasminogen Activator System and Pancreatic Stellate Cells
Oscar Joe Hines, MD
R21 CA 1207803 - Role of CXCr2 in Pancreatic Cancer
Other collaborative center grants and individual initiated grants are currently under consideration by NIH.
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