| Translational Research |
Ronald S. Hirshberg Translational Pancreatic Cancer Research Laboratory
Opened in February of 1998 at the University of California, Los Angeles' School of Medicine, the Lab engages in scientific research designed to:
Current Projects:
- Phytochemicals in pancreatic cancer therapy and prevention
- Antidiabetic strategies in pancreatic cancer
- Fish oil and pancreatic cancer
- Eicosanoids and pancreatic cancer
- Anti-inflammatory strategies for pancreatic cancer therapy and prevention
- Nuclear receptors in pancreatic cancer
- Chemokines and pancreatic cancer
- Orthotopic and transgenic animal models
Laboratory Director:
Howard A. Reber, M.D.
- Professor of Surgery & Chief, Section of Gastrointestinal Surgery, David Geffen School of Medicine at UCLA
- Director of Ronald S. Hirshberg Translational Pancreatic Cancer Research Laboratory
- Director of UCLA Center for Pancreatic Diseases
Laboratory Assistant Director:
Joe Hines, M.D.
- Assistant Professor of Surgery, UCLA School of Medicine
Scientific Director:
Guido Eibl, M.D.
- Principal Investigator and Technical Laboratory Director, Division of General Surgery, UCLA School of Medicine
Past and present laboratory fellows and staff:
1) Hubert Hotz (1998-1999)
2) Peter Buechler (1998-2000)
3) Nova Rider (1999-2000)
4) Diana Yoon (2000-2001)
5) Guido Eibl (2000-2002)
6) Moritz Wente (2000-2002)
7) Hirotaka Ohara (2001-2002)
8) Yuji Okada (2001-2003)
9) John Duffy (2001-2003)
10) Kevork Kazanjian (2003-2005)
11) Hirozumi Sawai (2004-2005)
12) Makoto Satake (2005-2007)
13) Hitoshi Funahashi (2005-2007) |
14) Sascha Hasan (2004-2006)
15) Elaine Angst (2007-2009)
16) Aihua Li (2007-2009)
17) Jenny Park (2008-2010)
19) Jonathon King (2008-2010)
18) Monica Chen (2008-present)
20) Aune Moro (2008-present)
21) Hiroki Takahashi (2008-present)
22) Stephanie Esquivel (2010 - present)
23) Mura Assifi (2010 - present)
24) Hung Pham (2009 - present)
25) Ethan Brovman (2010 - present)
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Current Funding:
| NIH/NCI |
R01 CA122042 (Pl: Eibl) |
| Dates: |
08/01/2007 - 05/31/2012 |
| Total Costs: |
$1,463,000 |
| Description: |
The role of n-3 polyunsaturated fatty acids in pancreatic cancer |
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This project is designed to explore the efficacy of n-3 polyunsaturated fatty acids in therapy and prevention of pancreatic cancer using xenograft and transgenic animal models of the disease. |
| NIH/NCCAM |
P01 AT003960 (Pl: Go) |
| Dates: |
09/30/2007 - 09/29/2012 |
| Total Costs: |
$5,997,080 |
| Description: |
UCLA Center for Excellence in Pancreatic Diseases |
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The overall goal of the Center is to evaluate the effects of phytonutrients, in particular polyphenolic compounds, on inflammatory and proliferative diseases of the pancreas, including diabetes, pancreatitis, and pancreatic cancer, using metabolomic methodology. The Center Grant funds studies in the Hirshberg Laboratory and the Pancreatic Research Group at the VA. |
Although encouraging strides are being made, pancreatic cancer research is urgently in need of increased funding. In fact it is estimate that only 52.7, million dollars of the National Cancer Institute’s (NCI) cancer research budget, will be spent on pancreatic cancer research this year. This is just a mere 1% of the NCI’s 4.824 billion dollar cancer research budget for 2002. Additionally, research spending per annual pancreatic cancer fatality only $1145 the lowest of any leading cancer.
Research spending per annual pancreatic cancer fatality only $1145 the lowest of any leading cancer.
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